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Targeted Delivery of Narrow-Spectrum Protein Antibiotics to the Lower Gastrointestinal Tract in a Murine Model of Escherichia coli Colonization

Bacteriocins are narrow-spectrum protein antibiotics that could potentially be used to engineer the human gut microbiota. However, technologies for targeted delivery of proteins to the lower gastrointestinal (GI) tract in preclinical animal models are currently lacking. In this work, we have develop...

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Detalles Bibliográficos
Autores principales: Carpena, Nuria, Richards, Kerry, Bello Gonzalez, Teresita D. J., Bravo-Blas, Alberto, Housden, Nicholas G., Gerasimidis, Konstantinos, Milling, Simon W. F., Douce, Gillian, Malik, Danish J., Walker, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551963/
https://www.ncbi.nlm.nih.gov/pubmed/34721311
http://dx.doi.org/10.3389/fmicb.2021.670535