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Targeted Delivery of Narrow-Spectrum Protein Antibiotics to the Lower Gastrointestinal Tract in a Murine Model of Escherichia coli Colonization
Bacteriocins are narrow-spectrum protein antibiotics that could potentially be used to engineer the human gut microbiota. However, technologies for targeted delivery of proteins to the lower gastrointestinal (GI) tract in preclinical animal models are currently lacking. In this work, we have develop...
Autores principales: | Carpena, Nuria, Richards, Kerry, Bello Gonzalez, Teresita D. J., Bravo-Blas, Alberto, Housden, Nicholas G., Gerasimidis, Konstantinos, Milling, Simon W. F., Douce, Gillian, Malik, Danish J., Walker, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551963/ https://www.ncbi.nlm.nih.gov/pubmed/34721311 http://dx.doi.org/10.3389/fmicb.2021.670535 |
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