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Prognostic Value of BIM Deletion in EGFR-Mutant NSCLC Patients Treated with EGFR-TKIs: A Meta-Analysis

BACKGROUND: Resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) is inevitable in EGFR-mutant non-small-cell lung cancer (NSCLC) patients. A germline 2903 bp deletion polymorphism of Bcl-2-like protein 11 (BIM) causes reduced expression of proapoptotic BH3-only BIM p...

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Detalles Bibliográficos
Autores principales: Lv, Fangfang, Sun, Liang, Yang, Qiuping, Pan, Zheng, Zhang, Yuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551980/
https://www.ncbi.nlm.nih.gov/pubmed/34722761
http://dx.doi.org/10.1155/2021/3621828