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Surface expression of the immunotherapeutic target G(D2) in osteosarcoma depends on cell confluency
BACKGROUND: Chimeric antigen receptor (CAR) T‐cell therapy of pediatric sarcomas is challenged by the paucity of targetable cell surface antigens. A candidate target in osteosarcoma (OS) is the ganglioside G(D2), but heterogeneous expression of G(D2) limits its value. AIM: We aimed to identify mecha...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551999/ https://www.ncbi.nlm.nih.gov/pubmed/33811471 http://dx.doi.org/10.1002/cnr2.1394 |