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Probing Single-Cell Macrophage Polarization and Heterogeneity Using Thermo-Reversible Hydrogels in Droplet-Based Microfluidics

Human immune cells intrinsically exist as heterogenous populations. To understand cellular heterogeneity, both cell culture and analysis should be executed with single-cell resolution to eliminate juxtacrine and paracrine interactions, as these can lead to a homogenized cell response, obscuring uniq...

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Detalles Bibliográficos
Autores principales: Tiemeijer, B. M., Sweep, M. W. D., Sleeboom, J. J. F., Steps, K. J., van Sprang, J. F., De Almeida, P., Hammink, R., Kouwer, P. H. J., Smits, A. I. P. M., Tel, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552120/
https://www.ncbi.nlm.nih.gov/pubmed/34722475
http://dx.doi.org/10.3389/fbioe.2021.715408