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Probing Single-Cell Macrophage Polarization and Heterogeneity Using Thermo-Reversible Hydrogels in Droplet-Based Microfluidics
Human immune cells intrinsically exist as heterogenous populations. To understand cellular heterogeneity, both cell culture and analysis should be executed with single-cell resolution to eliminate juxtacrine and paracrine interactions, as these can lead to a homogenized cell response, obscuring uniq...
Autores principales: | Tiemeijer, B. M., Sweep, M. W. D., Sleeboom, J. J. F., Steps, K. J., van Sprang, J. F., De Almeida, P., Hammink, R., Kouwer, P. H. J., Smits, A. I. P. M., Tel, J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552120/ https://www.ncbi.nlm.nih.gov/pubmed/34722475 http://dx.doi.org/10.3389/fbioe.2021.715408 |
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