Suppression of ventricular arrhythmias by targeting late L-type Ca(2+) current

Ventricular arrhythmias, a leading cause of sudden cardiac death, can be triggered by cardiomyocyte early afterdepolarizations (EADs). EADs can result from an abnormal late activation of L-type Ca(2+) channels (LTCCs). Current LTCC blockers (class IV antiarrhythmics), while effective at suppressing...

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Detalles Bibliográficos
Autores principales: Angelini, Marina, Pezhouman, Arash, Savalli, Nicoletta, Chang, Marvin G., Steccanella, Federica, Scranton, Kyle, Calmettes, Guillaume, Ottolia, Michela, Pantazis, Antonios, Karagueuzian, Hrayr S., Weiss, James N., Olcese, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552156/
https://www.ncbi.nlm.nih.gov/pubmed/34698805
http://dx.doi.org/10.1085/jgp.202012584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552156/
https://www.ncbi.nlm.nih.gov/pubmed/34698805
http://dx.doi.org/10.1085/jgp.202012584

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