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Targeting Estrogen Receptor-Positive Breast Microtumors with Endoxifen-Conjugated, Hypoxia-Sensitive Polymersomes

[Image: see text] Endoxifen is the primary active metabolite of tamoxifen, a nonsteroidal-selective estrogen receptor modulator (SERM) and widely used medication to treat estrogen receptor-positive (ER+) breast cancer. In this study, endoxifen was conjugated to the surface of polymeric nanoparticles...

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Detalles Bibliográficos
Autores principales: Mamnoon, Babak, Feng, Li, Froberg, Jamie, Choi, Yongki, Sathish, Venkatachalem, Taratula, Oleh, Taratula, Olena, Mallik, Sanku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552235/
https://www.ncbi.nlm.nih.gov/pubmed/34722965
http://dx.doi.org/10.1021/acsomega.1c02250