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5-Hydroxymethylfurfural Enhances the Antiviral Immune Response in Macrophages through the Modulation of RIG-I-Mediated Interferon Production and the JAK/STAT Signaling Pathway

[Image: see text] 5-Hydroxymethylfurfural (5-HMF) exists in a wide range of sugar-rich foods and traditional Chinese medicines. The role of 5-HMF in antiviral innate immunity and its mechanism have not been reported previously. In this study, we reveal for the first time that 5-HMF upregulates the p...

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Detalles Bibliográficos
Autores principales: Zou, Han, Wu, Tingyue, Wang, Yuan, Kang, Yanhua, Shan, Qingye, Xu, Liqing, Jiang, Zheyi, Lin, Xiaohan, Ye, Xiang-Yang, Xie, Tian, Zhang, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552330/
https://www.ncbi.nlm.nih.gov/pubmed/34723002
http://dx.doi.org/10.1021/acsomega.1c03862