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Design, synthesis, and initial immunological evaluation of glycoconjugates based on saponin adjuvants and the Tn antigen
We report the first synthesis and immunological evaluation of a new glycoconjugate design based on streamlined saponin adjuvants and the Tn carbohydrate antigen. While the novel synthetic constructs induced moderate antibody responses in mice, the versatile chemical platform is amenable to further s...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552335/ https://www.ncbi.nlm.nih.gov/pubmed/34647563 http://dx.doi.org/10.1039/d1cc04459a |