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Structural Ensemble of the Insulin Monomer
[Image: see text] Experimental evidence suggests that monomeric insulin exhibits significant conformational heterogeneity, and modifications of apparently disordered regions affect both biological activity and the longevity of pharmaceutical formulations, presumably through receptor binding and fibr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552439/ https://www.ncbi.nlm.nih.gov/pubmed/34637307 http://dx.doi.org/10.1021/acs.biochem.1c00583 |