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Structural Ensemble of the Insulin Monomer

[Image: see text] Experimental evidence suggests that monomeric insulin exhibits significant conformational heterogeneity, and modifications of apparently disordered regions affect both biological activity and the longevity of pharmaceutical formulations, presumably through receptor binding and fibr...

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Detalles Bibliográficos
Autores principales:	Busto-Moner, Luis, Feng, Chi-Jui, Antoszewski, Adam, Tokmakoff, Andrei, Dinner, Aaron R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552439/ https://www.ncbi.nlm.nih.gov/pubmed/34637307 http://dx.doi.org/10.1021/acs.biochem.1c00583

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