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Halogenated Coumarin–Chalcones as Multifunctional Monoamine Oxidase-B and Butyrylcholinesterase Inhibitors

[Image: see text] A series of halogenated coumarin–chalcones were synthesized, characterized, and their inhibitory activities against monoamine oxidases (MAOs), acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and β-site amyloid precursor protein cleaving enzyme 1 (BACE-1) were evaluated....

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Detalles Bibliográficos
Autores principales: Rehuman, Nisha Abdul, Oh, Jong Min, Nath, Lekshmi R., Khames, Ahmed, Abdelgawad, Mohamed A., Gambacorta, Nicola, Nicolotti, Orazio, Jat, Rakesh Kumar, Kim, Hoon, Mathew, Bijo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552465/
https://www.ncbi.nlm.nih.gov/pubmed/34723016
http://dx.doi.org/10.1021/acsomega.1c04252