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Short Synthesis of Molnupiravir (EIDD-2801) via a Thionated Uridine Intermediate
[Image: see text] Molnupiravir (MK-4482, EIDD-2801) is an experimental drug that has been demonstrated to be effective for the treatment of COVID-19 in human clinical trials. Herein, we report a concise synthesis of the drug via a novel thionated derivative that relies on one-pot methodologies, thus...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552467/ https://www.ncbi.nlm.nih.gov/pubmed/34723033 http://dx.doi.org/10.1021/acsomega.1c04550 |