Synthesis and Biological Evaluation of a c(RGDyK) Peptide Conjugate of SRPIN803

[Image: see text] In the present study, SRPIN803 and c(RGDyK)-SRPIN803 hybrid compounds were efficiently synthesized and evaluated for their stability in human plasma and buffers of pH 7.4 and 5.2. The hybrids were mainly cytostatic against a panel of tested cancer cells, whereas one c(RGDyK)-SRPIN8...

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Detalles Bibliográficos
Autores principales: Leonidis, George, Dalezis, Panagiotis, Trafalis, Dimitrios, Beis, Dimitris, Giardoglou, Panagiota, Koukiali, Anastasia, Sigala, Ioanna, Nikolakaki, Eleni, Sarli, Vasiliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552469/
https://www.ncbi.nlm.nih.gov/pubmed/34723035
http://dx.doi.org/10.1021/acsomega.1c04576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552469/
https://www.ncbi.nlm.nih.gov/pubmed/34723035
http://dx.doi.org/10.1021/acsomega.1c04576

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