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Construction of a Drug Delivery System via pH-Responsive Polymeric Nanomicelles Containing Ferrocene for DOX Release and Enhancement of Therapeutic Effects

[Image: see text] We report an amphiphilic block copolymer via poly(ethylene glycol) methyl ether-D(labile)-poly(caprolactone)-ferrocene (mPEG-D(labile)-PCL-Fc) to deliver anticancer drug doxorubicin (DOX). Lipase Novozyme-435 was used as a catalyst for ring-opening polymerization with ε-caprolacton...

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Detalles Bibliográficos
Autores principales: Song, Chenggang, Yang, Fan, Ji, Ruixuan, Lv, Yin, Wei, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552479/
https://www.ncbi.nlm.nih.gov/pubmed/34723021
http://dx.doi.org/10.1021/acsomega.1c04330