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A Versatile Human Intestinal Organoid-Derived Epithelial Monolayer Model for the Study of Enteric Pathogens

Gastrointestinal infections cause significant morbidity and mortality worldwide. The complexity of human biology and limited insights into host-specific infection mechanisms are key barriers to current therapeutic development. Here, we demonstrate that two-dimensional epithelial monolayers derived f...

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Detalles Bibliográficos
Autores principales: Nickerson, Kourtney P., Llanos-Chea, Alejandro, Ingano, Laura, Serena, Gloria, Miranda-Ribera, Alba, Perlman, Meryl, Lima, Rosiane, Sztein, Marcelo B., Fasano, Alessio, Senger, Stefania, Faherty, Christina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552518/
https://www.ncbi.nlm.nih.gov/pubmed/34106568
http://dx.doi.org/10.1128/spectrum.00003-21