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Single-Cell RNA Sequencing Reveals Cellular Heterogeneity and Stage Transition under Temperature Stress in Synchronized Plasmodium falciparum Cells

The malaria parasite has a complex life cycle exhibiting phenotypic and morphogenic variations in two different hosts by existing in heterogeneous developmental states. To investigate this cellular heterogeneity of the parasite within the human host, we performed single-cell RNA sequencing of synchr...

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Detalles Bibliográficos
Autores principales: Rawat, Mukul, Srivastava, Ashish, Johri, Shreya, Gupta, Ishaan, Karmodiya, Krishanpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552519/
https://www.ncbi.nlm.nih.gov/pubmed/34232098
http://dx.doi.org/10.1128/spectrum.00008-21