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Using soft X-ray tomography for rapid whole-cell quantitative imaging of SARS-CoV-2-infected cells

High-resolution and rapid imaging of host cell ultrastructure can generate insights toward viral disease mechanism, for example for a severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Here, we employ full-rotation soft X-ray tomography (SXT) to examine organelle remodeling indu...

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Detalles Bibliográficos
Autores principales: Loconte, Valentina, Chen, Jian-Hua, Cortese, Mirko, Ekman, Axel, Le Gros, Mark A., Larabell, Carolyn, Bartenschlager, Ralf, Weinhardt, Venera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552653/
https://www.ncbi.nlm.nih.gov/pubmed/34729550
http://dx.doi.org/10.1016/j.crmeth.2021.100117