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Deubiquitination and Activation of the NLRP3 Inflammasome by UCHL5 in HCV-Infected Cells

Chronic hepatitis C virus (HCV) infection induces liver inflammation that can lead to fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Inflammation is the outcome of the action of proinflammatory cytokines and chemokines, including interleukin-1 beta (IL-1β) and tumor necrosis factor alpha....

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Detalles Bibliográficos
Autores principales: Ramachandran, Akshaya, Kumar, Binod, Waris, Gulam, Everly, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552718/
https://www.ncbi.nlm.nih.gov/pubmed/34431717
http://dx.doi.org/10.1128/spectrum.00755-21