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TMPRSS2 and RNA-Dependent RNA Polymerase Are Effective Targets of Therapeutic Intervention for Treatment of COVID-19 Caused by SARS-CoV-2 Variants (B.1.1.7 and B.1.351)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a causative agent of the coronavirus disease 2019 (COVID-19) pandemic, and the development of therapeutic interventions is urgently needed. So far, monoclonal antibodies and drug repositioning are the main methods for drug development,...

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Detalles Bibliográficos
Autores principales: Lee, Jihye, Lee, JinAh, Kim, Hyeon Ju, Ko, Meehyun, Jee, Youngmee, Kim, Seungtaek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552736/
https://www.ncbi.nlm.nih.gov/pubmed/34378968
http://dx.doi.org/10.1128/spectrum.00472-21