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Structural Basis and Function of the N Terminus of SARS-CoV-2 Nonstructural Protein 1
Nonstructural protein 1 (Nsp1) of severe acute respiratory syndrome coronaviruses (SARS-CoVs) is an important pathogenic factor that inhibits host protein translation by means of its C terminus. However, its N-terminal function remains elusive. Here, we determined the crystal structure of the N term...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552758/ https://www.ncbi.nlm.nih.gov/pubmed/34132580 http://dx.doi.org/10.1128/spectrum.00169-21 |