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Time-Kill Evaluation of Antibiotic Combinations Containing Ceftazidime-Avibactam against Extensively Drug-Resistant Pseudomonas aeruginosa and Their Potential Role against Ceftazidime-Avibactam-Resistant Isolates

Ceftazidime-avibactam (CZA) has emerged as a promising solution to the lack of new antibiotics against Pseudomonas aeruginosa infections. Data from in vitro assays of CZA combinations, however, are scarce. The objective of our study was to perform a time-kill analysis of the effectiveness of CZA alo...

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Detalles Bibliográficos
Autores principales: Montero, María M., Domene Ochoa, Sandra, López-Causapé, Carla, Luque, Sonia, Sorlí, Luisa, Campillo, Núria, López Montesinos, Inmaculada, Padilla, Eduardo, Prim, Núria, Angulo-Brunet, Ariadna, Grau, Santiago, Oliver, Antonio, Horcajada, Juan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552783/
https://www.ncbi.nlm.nih.gov/pubmed/34319141
http://dx.doi.org/10.1128/spectrum.00585-21