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Effects of exercise on AKT/PGC1-α/FOXO3a pathway and muscle atrophy in cisplatin-administered rat skeletal muscle

Cisplatin has been reported to cause side effects such as muscle wasting in humans and rodents. The physiological mechanisms involved in preventing muscle wasting, such as the regulation of AKT, PGC1-α, and autophagy-related factor FOXO3a by MuRF 1 and Atrogin-1, remain unclear following different t...

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Detalles Bibliográficos
Autores principales: Bae, Jun Hyun, Seo, Dae Yun, Lee, Sang Ho, Shin, Chaeyoung, Jamrasi, Parivash, Han, Jin, Song, Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552830/
https://www.ncbi.nlm.nih.gov/pubmed/34697269
http://dx.doi.org/10.4196/kjpp.2021.25.6.585