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M1-type microglia can induce astrocytes to deposit chondroitin sulfate proteoglycan after spinal cord injury

After spinal cord injury (SCI), astrocytes gradually migrate to and surround the lesion, depositing chondroitin sulfate proteoglycan-rich extracellular matrix and forming astrocytic scar, which limits the spread of inflammation but hinders axon regeneration. Meanwhile, microglia gradually accumulate...

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Detalles Bibliográficos
Autores principales: Yu, Shui-Sheng, Li, Zi-Yu, Xu, Xin-Zhong, Yao, Fei, Luo, Yang, Liu, Yan-Chang, Cheng, Li, Zheng, Mei-Ge, Jing, Jue-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552861/
https://www.ncbi.nlm.nih.gov/pubmed/34558535
http://dx.doi.org/10.4103/1673-5374.324858