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Development and validation of a novel LC-MS/MS assay for C-peptide in human serum

INTRODUCTION:  C-peptide is used as a marker of endogenous insulin secretion in the assessment of residual β-cell function in diabetes and in the diagnostic workup of hypoglycemia. Previously developed LC-MS/MS methods to quantify serum concentrations of C-peptide have monitored intact peptide, whic...

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Detalles Bibliográficos
Autores principales: Owusu, Benjamin Y., Pflaum, Hannah, Garner, Russell, Foulon, North, Laha, Thomas J., Hoofnagle, Andrew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553002/
https://www.ncbi.nlm.nih.gov/pubmed/34723236
http://dx.doi.org/10.1016/j.jmsacl.2020.12.001