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Sortase-mediated segmental labeling: A method for segmental assignment of intrinsically disordered regions in proteins

A significant number of proteins possess sizable intrinsically disordered regions (IDRs). Due to the dynamic nature of IDRs, NMR spectroscopy is often the tool of choice for characterizing these segments. However, the application of NMR to IDRs is often hindered by their instability, spectral overla...

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Detalles Bibliográficos
Autores principales: Boyko, Kristina V., Rosenkranz, Erin A., Smith, Derrick M., Miears, Heather L., Oueld es cheikh, Melissa, Lund, Micah Z., Young, Jeffery C., Reardon, Patrick N., Okon, Mark, Smirnov, Serge L., Antos, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553144/
https://www.ncbi.nlm.nih.gov/pubmed/34710113
http://dx.doi.org/10.1371/journal.pone.0258531