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Transcriptional dynamics in the protozoan parasite Sarcocystis neurona and mammalian host cells after treatment with a specific inhibitor of apicomplexan mRNA polyadenylation

In recent years, a class of chemical compounds (benzoxaboroles) that are active against a range of parasites has been shown to target mRNA polyadenylation by inhibiting the activity of CPSF73, the endonucleolytic core of the eukaryotic polyadenylation complex. One particular compound, termed AN3661,...

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Detalles Bibliográficos
Autores principales: Hunt, Arthur G., Howe, Daniel K., Brown, Ashley, Yeargan, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553156/
https://www.ncbi.nlm.nih.gov/pubmed/34710156
http://dx.doi.org/10.1371/journal.pone.0259109