Microbiota-Host-Irinotecan Axis: A New Insight Toward Irinotecan Chemotherapy

Irinotecan (CPT11) and its active metabolite ethyl-10-hydroxy-camptothecin (SN38) are broad-spectrum cytotoxic anticancer agents. Both cause cell death in rapidly dividing cells (e.g., cancer cells, epithelial cells, hematopoietic cells) and commensal bacteria. Therefore, CPT11 can induce a series o...

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Detalles Bibliográficos
Autores principales: Yue, Bei, Gao, Ruiyang, Wang, Zhengtao, Dou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553258/
https://www.ncbi.nlm.nih.gov/pubmed/34722328
http://dx.doi.org/10.3389/fcimb.2021.710945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553258/
https://www.ncbi.nlm.nih.gov/pubmed/34722328
http://dx.doi.org/10.3389/fcimb.2021.710945

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