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Improving properties of the nucleobase analogs T-705/T-1105 as potential antiviral

In this minireview we describe our work on the improvement of the nucleobase analogs Favipiravir (T-705) und its non-fluorinated derivative T-1105 as influenza and SARS-CoV-2 active compounds. Both nucleobases were converted into nucleotides and then included in our nucleotide prodrugs technologies...

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Detalles Bibliográficos
Autores principales: Jia, Xiao, Ganter, Benedikt, Meier, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553380/
https://www.ncbi.nlm.nih.gov/pubmed/34728864
http://dx.doi.org/10.1016/bs.armc.2021.08.002