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Pharmacokinetics and Toxicokinetics of Artemisinin-Hydroxychloroquine Sulfate Tablets in Rats and Dogs

Artemisinin-hydroxychloroquine sulfate tablets (AH) are relatively inexpensive and a novel combination therapy for the treatment of all forms of malaria, especially aminoquinine drug-resistant strains of P. falciparum. Our aim was to assess the pharmacokinetics (PK) and toxicokinetics (TK) of AH fol...

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Detalles Bibliográficos
Autores principales: Li, Xiaobo, Hu, Jiaoting, Yuan, Yueming, Wang, Yunhan, Yuan, Zheng, Liu, Ruidong, Zhang, Shouya, Xu, Zhiyong, Wang, Qi, Xu, Qin, Ru, Li, Song, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553450/
https://www.ncbi.nlm.nih.gov/pubmed/34721641
http://dx.doi.org/10.1155/2021/6830459