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Metabolite Profiling of Meridianin C In Vivo of Rat by UHPLC/Q-TOF MS

Meridianin C (MC), as a marine alkaloid, is a potent protein kinase inhibitor which exhibits good anticancer activity. However, the in vivo metabolism of MC has not been described to date. In this study, an ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UHP...

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Detalles Bibliográficos
Autores principales: Zhang, Guozhe, Xiao, Linxia, Qi, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553504/
https://www.ncbi.nlm.nih.gov/pubmed/34721922
http://dx.doi.org/10.1155/2021/1382421