Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model

Cortical spreading depression (CSD), a wave of depolarization followed by depression of cortical activity, is a pathophysiological process implicated in migraine with aura and various other brain pathologies, such as ischemic stroke and traumatic brain injury. To gain insight into the pathophysiolog...

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Detalles Bibliográficos
Autores principales: Auffenberg, Eva, Hedrich, Ulrike B.S., Barbieri, Raffaella, Miely, Daniela, Groschup, Bernhard, Wuttke, Thomas V., Vogel, Niklas, Lührs, Philipp, Zanardi, Ilaria, Bertelli, Sara, Spielmann, Nadine, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabě de Angelis, Martin, Pusch, Michael, Dichgans, Martin, Lerche, Holger, Gavazzo, Paola, Plesnila, Nikolaus, Freilinger, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553559/
https://www.ncbi.nlm.nih.gov/pubmed/34546973
http://dx.doi.org/10.1172/JCI142202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553559/
https://www.ncbi.nlm.nih.gov/pubmed/34546973
http://dx.doi.org/10.1172/JCI142202

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