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UV Resonance Raman explores protein structural modification upon fibrillation and ligand interaction

Amyloids are proteinaceous deposits considered an underlying pathological hallmark of several degenerative diseases. The mechanism of amyloid formation and its inhibition still represent challenging issues, especially when protein structure cannot be investigated by classical biophysical techniques...

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Detalles Bibliográficos
Autores principales: Pachetti, Maria, D’Amico, Francesco, Pascolo, Lorella, Pucciarelli, Stefania, Gessini, Alessandro, Parisse, Pietro, Vaccari, Lisa, Masciovecchio, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553600/
https://www.ncbi.nlm.nih.gov/pubmed/34474016
http://dx.doi.org/10.1016/j.bpj.2021.08.032