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UV Resonance Raman explores protein structural modification upon fibrillation and ligand interaction
Amyloids are proteinaceous deposits considered an underlying pathological hallmark of several degenerative diseases. The mechanism of amyloid formation and its inhibition still represent challenging issues, especially when protein structure cannot be investigated by classical biophysical techniques...
Autores principales: | Pachetti, Maria, D’Amico, Francesco, Pascolo, Lorella, Pucciarelli, Stefania, Gessini, Alessandro, Parisse, Pietro, Vaccari, Lisa, Masciovecchio, Claudio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553600/ https://www.ncbi.nlm.nih.gov/pubmed/34474016 http://dx.doi.org/10.1016/j.bpj.2021.08.032 |
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