Increased BUB1B/BUBR1 expression contributes to aberrant DNA repair activity leading to resistance to DNA-damaging agents

There has been accumulating evidence for the clinical benefit of chemoradiation therapy (CRT), whereas mechanisms in CRT-recurrent clones derived from the primary tumor are still elusive. Herein, we identified an aberrant BUB1B/BUBR1 expression in CRT-recurrent clones in bladder cancer (BC) by compr...

Descripción completa

Detalles Bibliográficos
Autores principales: Komura, Kazumasa, Inamoto, Teruo, Tsujino, Takuya, Matsui, Yusuke, Konuma, Tsuyoshi, Nishimura, Kazuki, Uchimoto, Taizo, Tsutsumi, Takeshi, Matsunaga, Tomohisa, Maenosono, Ryoichi, Yoshikawa, Yuki, Taniguchi, Kohei, Tanaka, Tomohito, Uehara, Hirofumi, Hirata, Koichi, Hirano, Hajime, Nomi, Hayahito, Hirose, Yoshinobu, Ono, Fumihito, Azuma, Haruhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553621/
https://www.ncbi.nlm.nih.gov/pubmed/34545188
http://dx.doi.org/10.1038/s41388-021-02021-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553621/
https://www.ncbi.nlm.nih.gov/pubmed/34545188
http://dx.doi.org/10.1038/s41388-021-02021-y

Ejemplares similares