SARS-CoV-2 spike protein causes blood coagulation and thrombosis by competitive binding to heparan sulfate

Thrombotic complication has been an important symptom in critically ill patients with COVID-19. It has not been clear whether the virus spike (S) protein can directly induce blood coagulation in addition to inflammation. Heparan sulfate (HS)/heparin, a key factor in coagulation process, was found to...

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Detalles Bibliográficos
Autores principales: Zheng, Yi, Zhao, Jinxiang, Li, Jiaqi, Guo, Zhimou, Sheng, Jiajing, Ye, Xianlong, Jin, Gaowa, Wang, Chaoran, Chai, Wengang, Yan, Jingyu, Liu, Dong, Liang, Xinmiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553634/
https://www.ncbi.nlm.nih.gov/pubmed/34743814
http://dx.doi.org/10.1016/j.ijbiomac.2021.10.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553634/
https://www.ncbi.nlm.nih.gov/pubmed/34743814
http://dx.doi.org/10.1016/j.ijbiomac.2021.10.112

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