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SARS-CoV-2 spike protein causes blood coagulation and thrombosis by competitive binding to heparan sulfate
Thrombotic complication has been an important symptom in critically ill patients with COVID-19. It has not been clear whether the virus spike (S) protein can directly induce blood coagulation in addition to inflammation. Heparan sulfate (HS)/heparin, a key factor in coagulation process, was found to...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553634/ https://www.ncbi.nlm.nih.gov/pubmed/34743814 http://dx.doi.org/10.1016/j.ijbiomac.2021.10.112 |