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SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System

Astrocytes, the main supportive cell type of the brain, show functional impairments upon ageing and in a broad spectrum of neurological disorders. Limited access to human astroglia for pre-clinical studies has been a major bottleneck delaying our understanding of their role in brain health and disea...

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Detalles Bibliográficos
Autores principales: Neyrinck, Katrien, Van Den Daele, Johanna, Vervliet, Tim, De Smedt, Jonathan, Wierda, Keimpe, Nijs, Melissa, Vanbokhoven, Tom, D’hondt, Astrid, Planque, Mélanie, Fendt, Sarah-Maria, Shih, Pei-Yu, Seibt, Frederik, Almenar, Juan Pita, Kreir, Mohamed, Kumar, Devesh, Broccoli, Vania, Bultynck, Geert, Ebneth, Andreas, Cabrera-Socorro, Alfredo, Verfaillie, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553725/
https://www.ncbi.nlm.nih.gov/pubmed/33982246
http://dx.doi.org/10.1007/s12015-021-10179-x