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SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System
Astrocytes, the main supportive cell type of the brain, show functional impairments upon ageing and in a broad spectrum of neurological disorders. Limited access to human astroglia for pre-clinical studies has been a major bottleneck delaying our understanding of their role in brain health and disea...
Autores principales: | Neyrinck, Katrien, Van Den Daele, Johanna, Vervliet, Tim, De Smedt, Jonathan, Wierda, Keimpe, Nijs, Melissa, Vanbokhoven, Tom, D’hondt, Astrid, Planque, Mélanie, Fendt, Sarah-Maria, Shih, Pei-Yu, Seibt, Frederik, Almenar, Juan Pita, Kreir, Mohamed, Kumar, Devesh, Broccoli, Vania, Bultynck, Geert, Ebneth, Andreas, Cabrera-Socorro, Alfredo, Verfaillie, Catherine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553725/ https://www.ncbi.nlm.nih.gov/pubmed/33982246 http://dx.doi.org/10.1007/s12015-021-10179-x |
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