Specialized transendothelial dendritic cells mediate thymic T-cell selection against blood-borne macromolecules

T cells undergo rigorous selection in the thymus to ensure self-tolerance and prevent autoimmunity, with this process requiring innocuous self-antigens (Ags) to be presented to thymocytes. Self-Ags are either expressed by thymic stroma cells or transported to the thymus from the periphery by migrato...

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Detalles Bibliográficos
Autores principales: Vollmann, Elisabeth H., Rattay, Kristin, Barreiro, Olga, Thiriot, Aude, Fuhlbrigge, Rebecca A., Vrbanac, Vladimir, Kim, Ki-Wook, Jung, Steffen, Tager, Andrew M., von Andrian, Ulrich H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553756/
https://www.ncbi.nlm.nih.gov/pubmed/34711828
http://dx.doi.org/10.1038/s41467-021-26446-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553756/
https://www.ncbi.nlm.nih.gov/pubmed/34711828
http://dx.doi.org/10.1038/s41467-021-26446-x

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