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Specialized transendothelial dendritic cells mediate thymic T-cell selection against blood-borne macromolecules
T cells undergo rigorous selection in the thymus to ensure self-tolerance and prevent autoimmunity, with this process requiring innocuous self-antigens (Ags) to be presented to thymocytes. Self-Ags are either expressed by thymic stroma cells or transported to the thymus from the periphery by migrato...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553756/ https://www.ncbi.nlm.nih.gov/pubmed/34711828 http://dx.doi.org/10.1038/s41467-021-26446-x |