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Microenvironmental IL-6 inhibits anti-cancer immune responses generated by cytotoxic chemotherapy

Cytotoxic chemotherapeutics primarily function through DNA damage-induced tumor cell apoptosis, although the inflammation provoked by these agents can stimulate anti-cancer immune responses. The mechanisms that control these distinct effects and limit immunogenic responses to DNA-damage mediated cel...

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Detalles Bibliográficos
Autores principales: Bent, Eric H., Millán-Barea, Luis R., Zhuang, Iris, Goulet, Daniel R., Fröse, Julia, Hemann, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553783/
https://www.ncbi.nlm.nih.gov/pubmed/34711820
http://dx.doi.org/10.1038/s41467-021-26407-4