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Microenvironmental IL-6 inhibits anti-cancer immune responses generated by cytotoxic chemotherapy
Cytotoxic chemotherapeutics primarily function through DNA damage-induced tumor cell apoptosis, although the inflammation provoked by these agents can stimulate anti-cancer immune responses. The mechanisms that control these distinct effects and limit immunogenic responses to DNA-damage mediated cel...
Autores principales: | Bent, Eric H., Millán-Barea, Luis R., Zhuang, Iris, Goulet, Daniel R., Fröse, Julia, Hemann, Michael T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553783/ https://www.ncbi.nlm.nih.gov/pubmed/34711820 http://dx.doi.org/10.1038/s41467-021-26407-4 |
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