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Loss of hepatic Flcn protects against fibrosis and inflammation by activating autophagy pathways

Non-alcoholic fatty liver disease (NAFLD) is the most frequent liver disease worldwide and can progress to non-alcoholic steatohepatitis (NASH), which is characterized by triglyceride accumulation, inflammation, and fibrosis. No pharmacological agents are currently approved to treat these conditions...

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Detalles Bibliográficos
Autores principales: Paquette, Mathieu, Yan, Ming, Ramírez-Reyes, Josué M. J., El-Houjeiri, Leeanna, Biondini, Marco, Dufour, Catherine R., Jeong, Hyeonju, Pacis, Alain, Giguère, Vincent, Estall, Jennifer L., Siegel, Peter M., Audet-Walsh, Étienne, Pause, Arnim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553785/
https://www.ncbi.nlm.nih.gov/pubmed/34711912
http://dx.doi.org/10.1038/s41598-021-99958-7