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Sperm epigenetic alterations contribute to inter- and transgenerational effects of paternal exposure to long-term psychological stress via evading offspring embryonic reprogramming
Paternal life experiences impact offspring health via germline, and epigenetic inheritance provides a potential mechanism. However, global reprogramming during offspring embryogenesis and gametogenesis represents the largest hurdle to conceptualize it. Yet, detailed characterization of how sperm epi...
Autores principales: | Zheng, Xiaoguo, Li, Zhenhua, Wang, Guishuan, Wang, Hanshu, Zhou, Yuchuan, Zhao, Xinzhi, Cheng, C. Yan, Qiao, Yunbo, Sun, Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553786/ https://www.ncbi.nlm.nih.gov/pubmed/34711814 http://dx.doi.org/10.1038/s41421-021-00343-5 |
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