Age-related neurodegeneration and cognitive impairments of NRMT1 knockout mice are preceded by misregulation of RB and abnormal neural stem cell development

N-terminal methylation is an important posttranslational modification that regulates protein/DNA interactions and plays a role in many cellular processes, including DNA damage repair, mitosis, and transcriptional regulation. Our generation of a constitutive knockout mouse for the N-terminal methyltr...

Descripción completa

Detalles Bibliográficos
Autores principales: Catlin, James P., Marziali, Leandro N., Rein, Benjamin, Yan, Zhen, Feltri, M. Laura, Schaner Tooley, Christine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553844/
https://www.ncbi.nlm.nih.gov/pubmed/34711807
http://dx.doi.org/10.1038/s41419-021-04316-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553844/
https://www.ncbi.nlm.nih.gov/pubmed/34711807
http://dx.doi.org/10.1038/s41419-021-04316-0

Ejemplares similares