Ion-dependent structure, dynamics, and allosteric coupling in a non-selective cation channel

The selectivity filter (SF) determines which ions are efficiently conducted through ion channel pores. NaK is a non-selective cation channel that conducts Na(+) and K(+) with equal efficiency. Crystal structures of NaK suggested a rigid SF structure, but later solid-state NMR and MD simulations ques...

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Detalles Bibliográficos
Autores principales: Lewis, Adam, Kurauskas, Vilius, Tonelli, Marco, Henzler-Wildman, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553846/
https://www.ncbi.nlm.nih.gov/pubmed/34711838
http://dx.doi.org/10.1038/s41467-021-26538-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553846/
https://www.ncbi.nlm.nih.gov/pubmed/34711838
http://dx.doi.org/10.1038/s41467-021-26538-8

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