Pancreatic cancer cells render tumor-associated macrophages metabolically reprogrammed by a GARP and DNA methylation-mediated mechanism

How tumor-associated macrophages transit from a predominant antitumor M1-like phenotype to a protumoral M2-like phenotype during the development of pancreatic ductal adenocarcinoma (PDA) remains to be elucidated. We thus conducted a study by employing a PDA-macrophage co-culture system, an “orthotop...

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Detalles Bibliográficos
Autores principales: Zhang, Mengwen, Pan, Xingyi, Fujiwara, Kenji, Jurcak, Noelle, Muth, Stephen, Zhou, Jiaojiao, Xiao, Qian, Li, Anqi, Che, Xu, Li, Zihai, Zheng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553927/
https://www.ncbi.nlm.nih.gov/pubmed/34711804
http://dx.doi.org/10.1038/s41392-021-00769-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553927/
https://www.ncbi.nlm.nih.gov/pubmed/34711804
http://dx.doi.org/10.1038/s41392-021-00769-z

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