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Transcriptomic analysis of loss of Gli1 in neural stem cells responding to demyelination in the mouse brain

In the adult mammalian brain, Gli1 expressing neural stem cells reside in the subventricular zone and their progeny are recruited to sites of demyelination in the white matter where they generate new oligodendrocytes, the myelin forming cells. Remarkably, genetic loss or pharmacologic inhibition of...

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Detalles Bibliográficos
Autores principales: Samanta, Jayshree, Silva, Hernandez Moura, Lafaille, Juan J., Salzer, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553940/
https://www.ncbi.nlm.nih.gov/pubmed/34711861
http://dx.doi.org/10.1038/s41597-021-01063-x